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What Does a Nephrologist Actually Do?

December 5, 2025

A nephrologist hold in one hand, a model of the human kidney, and in other a stethoscope.

In short,

  • A nephrologist is a medical doctor who specializes in diagnosing and treating kidney diseases, managing conditions from kidney stones to kidney failure.
  • Nephrologists help patients manage chronic conditions like diabetes and high blood pressure that can damage the kidneys over time.
  • Early referral to a nephrologist when kidney problems are detected can slow disease progression and prevent the need for dialysis.

Understanding Nephrology and Kidney Health

Nephrology is the medical specialty focused on kidney health, disease prevention, diagnosis, and treatment. A nephrologist is a physician who has completed specialized training in managing the complex conditions that affect kidney function.

Your kidneys perform essential life-sustaining functions every day. These bean-shaped organs filter waste products and excess fluid from your blood, regulate blood pressure, maintain proper electrolyte balance, and activate vitamin D for calcium absorption and bone health. When kidneys do not function properly, waste products accumulate in the body and serious health problems can develop.

Nephrologists work to preserve kidney function, manage kidney disease progression, and coordinate care when kidney replacement therapy becomes necessary.

The Critical Role Kidneys Play in Your Body

Understanding what your kidneys do helps explain why nephrologists focus on protecting these vital organs.

Your kidneys filter approximately 200 quarts of blood daily, producing one to two quarts of urine that carries away waste products and excess water. This filtration process removes toxins, drugs, and metabolic waste while retaining essential proteins and nutrients your body needs.

The kidneys regulate blood pressure through multiple mechanisms, including controlling fluid volume and producing hormones that affect blood vessel constriction. They maintain precise electrolyte balance by adjusting how much sodium, potassium, calcium, and phosphorus is retained or excreted.

The kidneys also activate vitamin D into its usable form, which is essential for calcium absorption and maintaining strong bones.

Common Kidney Diseases Nephrologists Treat

Nephrologists diagnose and manage a wide range of kidney conditions, from acute problems to chronic progressive diseases.

Chronic Kidney Disease

Chronic kidney disease involves a gradual loss of kidney function over months or years. This progressive condition can eventually lead to kidney failure requiring dialysis or transplant if not properly managed. Early intervention can significantly slow disease progression.

Kidney Stones

Kidney stones are hard deposits of minerals and salts that form inside the kidneys. While small stones may pass on their own, larger stones can cause severe pain and may require intervention. Nephrologists help identify underlying causes and prevent recurrence.

Glomerulonephritis

Glomerulonephritis is inflammation of the glomeruli, the tiny filtering units within the kidneys. This condition can result from infections, autoimmune diseases, or other causes and may lead to kidney damage if untreated.

Polycystic Kidney Disease

Polycystic kidney disease is an inherited disorder causing numerous fluid-filled cysts to develop in the kidneys. These cysts gradually enlarge and can eventually impair kidney function. Genetic mutations in the PKD1 and PKD2 genes are responsible for most cases.

Risk Factors for Kidney Disease

Certain medical conditions, lifestyle factors, and genetic predispositions increase the likelihood of developing kidney disease.

Underlying Medical Conditions

Diabetes is one of the leading causes of kidney disease, as high blood sugar levels damage the delicate blood vessels in the kidneys over time. Hypertension strains and damages the kidneys through sustained high pressure in the kidney’s blood vessels. Heart disease reduces blood flow to the kidneys, potentially impairing their function.

Managing these chronic conditions through medication and lifestyle changes is crucial for preventing or slowing kidney disease development.

Lifestyle and Environmental Factors

Obesity increases the risk of developing both diabetes and hypertension, which are major risk factors. Smoking damages blood vessels throughout the body, including those in the kidneys, accelerating kidney function decline.

Long-term use of certain medications, particularly nonsteroidal anti-inflammatory drugs like ibuprofen, can harm the kidneys when used regularly over extended periods. Always discuss medication risks with your healthcare provider.

Family History and Genetics

Having a family history of kidney disease increases your risk of developing kidney problems. Specific genetic mutations can directly cause kidney disease, as seen in polycystic kidney disease and certain forms of glomerulonephritis. Discussing your family history with your healthcare provider enables early detection and proactive management.

Recognizing Symptoms of Kidney Disease

Kidney disease often develops silently in its early stages, making regular screening important for at-risk individuals.

Early Warning Signs

Persistent fatigue may develop as the kidneys produce less erythropoietin, a hormone that stimulates red blood cell production. Changes in urination patterns, including increased or decreased frequency, foamy urine, or blood in the urine, warrant medical evaluation.

Swelling in the ankles, feet, and hands occurs when the kidneys cannot remove excess fluid effectively.

Advanced Symptoms

As kidney disease progresses, more severe symptoms emerge. Nausea and vomiting result from the buildup of waste products in the blood, a condition called uremia. Loss of appetite and changes in taste can occur as uremia affects the digestive system.

Muscle cramps develop due to electrolyte imbalances that the failing kidneys cannot correct. Severe itching results from waste products accumulating in the skin.

These advanced symptoms indicate significant kidney damage requiring immediate medical attention from a nephrologist.

How Nephrologists Diagnose Kidney Disease

Nephrologists use a comprehensive approach to evaluate kidney function and identify specific kidney diseases.

Medical History and Physical Examination

Your nephrologist will review your medical history, including past illnesses, current medications, and family history of kidney disease. The physical examination checks for signs of fluid retention, high blood pressure, and other indicators of kidney problems.

Laboratory Testing

Blood tests measure creatinine and blood urea nitrogen levels to assess how efficiently your kidneys are filtering waste. The estimated glomerular filtration rate provides a measure of overall kidney function and helps stage chronic kidney disease.

Urine tests analyze for protein, blood, glucose, and other abnormalities that indicate kidney damage or disease. An electrolyte panel assesses levels of sodium, potassium, calcium, and phosphorus to detect imbalances that the kidneys should regulate.

Imaging and Specialized Tests

Ultrasound imaging can detect kidney cysts, stones, or structural abnormalities. CT scans provide more detailed images when needed to evaluate complex problems.

A kidney biopsy, which involves removing a small tissue sample for microscopic examination, helps diagnose specific types of kidney disease when the cause remains unclear.

Treatment Approaches Nephrologists Use

Nephrologists develop comprehensive treatment plans tailored to each patient’s specific condition and stage of kidney disease.

Medical Management

Medications help control conditions that affect kidney health. ACE inhibitors and ARBs lower blood pressure and provide kidney protection, though they require monitoring for potential side effects like elevated potassium levels.

Diuretics reduce fluid retention and help control blood pressure, but need careful monitoring of electrolytes and kidney function.

Phosphate binders help lower phosphorus levels in patients with chronic kidney disease, as the kidneys lose their ability to eliminate excess phosphorus. Erythropoiesis-stimulating agents treat anemia caused by reduced kidney production of erythropoietin, though these medications carry potential risks and require close monitoring.

Always consult with your nephrologist about potential side effects and necessary monitoring when taking these medications.

Dietary Modifications

Nephrologists often recommend dietary changes to reduce the workload on your kidneys and manage complications. Limiting sodium intake to less than 2,300 milligrams per day helps control blood pressure and fluid retention. Choosing lean protein sources and moderating overall protein intake reduces the waste products kidneys must filter.

Avoiding processed foods helps limit sodium and phosphorus intake. For patients with advanced kidney disease, carefully managing potassium intake becomes important, as high potassium levels can be dangerous when the kidneys cannot excrete it properly.

Working with a registered dietitian who specializes in kidney disease ensures you receive adequate nutrition while following kidney-protective guidelines.

Kidney Replacement Therapy

When kidney function declines to the point where the kidneys can no longer sustain life, kidney replacement therapy becomes necessary. Dialysis mechanically filters waste products and excess fluid from the blood, with hemodialysis and peritoneal dialysis as the two main types.

Kidney transplantation replaces the diseased kidney with a healthy donor kidney, offering the best quality of life for eligible patients. Nephrologists coordinate care before, during, and after transplantation.

Preventing Kidney Disease

Many cases of kidney disease can be prevented or delayed through proactive health management.

Controlling diabetes by keeping blood sugar within target ranges protects the kidneys from high glucose damage. Managing hypertension through medication and lifestyle changes prevents kidney damage from sustained high blood pressure.

Regular exercise, aiming for at least 30 minutes of moderate activity most days, helps maintain a healthy weight and blood pressure. Eating a balanced diet rich in fruits, vegetables, and whole grains while limiting processed foods supports overall kidney health. Maintaining a healthy weight reduces the risk of developing diabetes and hypertension. Quitting smoking is essential, as tobacco use accelerates kidney disease progression.

Staying properly hydrated helps your kidneys function optimally, though patients with certain kidney conditions may need to restrict fluid intake as directed by their nephrologist. Avoiding excessive use of over-the-counter pain medications, particularly NSAIDs, protects kidney function.

When to See a Nephrologist

You should seek nephrology care if you experience symptoms of kidney disease or have risk factors that make kidney problems more likely. Early detection and management can slow disease progression and improve long-term outcomes.

Your primary care physician may refer you to a nephrologist if blood or urine tests show declining kidney function, persistent protein in your urine, or difficult-to-control high blood pressure that may have a kidney-related cause.

Emergency Warning Signs

Seek immediate medical attention if you experience a sudden decrease in urine output, severe flank pain, blood in your urine, difficulty breathing, or confusion and altered mental status. These symptoms may indicate acute kidney injury or other serious complications requiring urgent treatment.

Questions to Ask Your Nephrologist

When meeting with a nephrologist, consider asking about your kidney disease stage and what it means for your health. Inquire about lifestyle changes that can slow disease progression and your available treatment options.

Ask about potential medication side effects and necessary monitoring. Find out how often you should have your kidney function tested and what the results mean. Understanding your condition empowers you to take an active role in protecting your kidney health.

Find Expert Nephrology Care in Brockton, MA

If you have concerns about your kidney health, have been diagnosed with kidney disease, or have risk factors like diabetes or high blood pressure, consultation with a nephrologist at Associates in Nephrology can provide specialized care focused on preserving your kidney function and overall health.

Call us today at (508) 587-0700 or use our online appointment request form to schedule a consultation and discuss your kidney health needs.

Filed Under: Nephrologist Tagged With: chronic kidney disease, Glomerulonephritis, Kidney Health, Kidney Replacement Therapy, kidney specialist near me, kidney stones, Medical Management, nephrology, Nephrology Care in Brockton, Symptoms of Kidney Disease

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Our kidney care specialists at Associates in Nephrology specialized training and experience needed to diagnose and treat kidney conditions such as Chronic Kidney Disease, Electrolyte Disorders, End-Stage Kidney Disease, Glomerulonephritis, Hypertension, Kidney Stones, Kidney Transplant, and Renal Failure. Contact us at (508) 587-0700 or request an appointment online to visit our kidney centers.